Toxicology (TGO)

Toxicology is the science that studies the undesirable and harmful effects of chemicals on the human body.

ADC’s Department of Toxicology and Drug Research (TGO) is since june 2016, NEN-EN-ISO 15189:2012 accredited under the ‘Raad voor Accreditatie’ (RvA) registration number M297, for the actions described in the scope: https://www.rva.nl/. This department is engaged in:

  • Judicial Inquiry;
  • Clinical & Forensic Toxicology ;
  • Drug research;
  • Clinical pharmaceutical research;
  • Comparative Research;
  • Water Research

 

Judicial Inquiry

Judicial Inquiry is one of the key tasks of TGO. Upon request from the police, customs and/or the Public Prosecution Service, research is conducted to find substances listed in the Opium Ordinance 1960 – particularly ‘street drugs’ and ‘designer drugs’. The identity – and potency – of the drug is determined on the basis of a variety of analytical chemical techniques.

 

 

Clinical-toxicological testing

  • Clinical Toxicology  testing is usually required when a patient ingests an unknown or an excessive amount of a substance – either accidentally or deliberately. This testing is particularly necessary in order to determine what and how much of the substance is absorbed in the blood or urine in order to treat the patient.
  • Clinical-toxicological screens may include the entire spectrum of available medicines and drugs, such as: cocaine, amphetamines (XTC), opiates, paracetamol, salicylic acid, alcohols and GHB. The test identifies and quantifies these substances precisely.

Forensic Toxicology testing

Forensic Toxicology Testing are toxicology tests for the purpose of aiding a legal investigation or court case. These tests are usually needed in order to potentially determine the extent which harmful substances have contributed to for instance, driving-under-the influence or traffic accidents, unnatural death or intoxication. Bodily fluids are tested: blood and or urine. The test will determine if the concentration of substances explain the cause of death of the victim.

Drugs & Pharmaceutical Research

Drugs & Pharmaceutical Research focuses on the pharmaceutical quality of drugs that are newly introduced by the Drug Registration Committee of Curaçao. Pharmaceutical analytical research is absolutely needed in order to introduce the newly registered drug. Locally prepared pharmaceutical medicines and pharmaceutical raw materials are also analyzed.

Clinical Pharmaceutical Research

Clinical Pharmaceutical Research determines the therapeutic concentration of a drug in the bodily material (usually blood). The goal is to optimize the effect of the drug, also called Therapeutic Drug Monitoring (TDM). This is applied during treatment of epilepsy, manic depression or rejections after transplants.

Food and Drug Administration

Food and Drug Administration is performed upon request of local or foreign producers. Various methods and techniques are used to determine the qualitative and quantitative concentration of specific substances, such as methanol, acetone, tertiary butyl alcohol and bitrex. It also determines the ethanol content in alcoholic beverages.

Water Research

Water intended for human consumption must meet the conditions described in the National Decree on Quality of Drinking Water (Pb. 2006 No. 72 of 12 September 2006). These conditions deal with the quality and delivery of water for human consumption. This department has been NEN-EN-ISO/IEC 17025:2005 accredited since March 25, 2009, by the ‘Raad voor Accreditatie’ (RvA) under registration number L493 for the operations described in the scope: https://www.rva.nl/.